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Faculty Research Areas

Molecular Cell Biology & Molecular Genetics

Dellaire, G. Nuclear structure and cancer biology; chemotherapy resistance and cancer biomarkers; CRISPR genome engineering; the role of nuclear organization in DNA repair, tumour suppression, and cell cycle control; genome instability and pre-mRNA splicing; zebrafish as a novel animal tumour model.
Dobson, M. J. Yeast and Mammalian Molecular Genetics
Duncan, R. Protein-mediated cell-cell membrane fusion during viral infections and muscle cell differentiation; viral fusion protein structure and function; cellular pathways involved in cell-cell fusion; exosomes and nonenveloped virus transmission; oncolytic viruses for tumour therapy.
Kienesberger, P. C. My research focuses on understanding molecular mechanisms of metabolic disorders. Specifically, I am investigating the role of lipid metabolism and signalling in the development of obesity and diabetes-related comorbidities.
Marignani, P. A. Tumour suppressors, Cancer metabolism, Metabolome wide analysis, Signal Transduction, Animal models of human disease, Pre-clinical drug studies, Drug discovery, Whole genome manipulation, Stem cell biology, Epigenetic marks.
McMaster, C. R. Genetics and chemical genetics to identify drug targets and drugs for unmet medical needs
Ro, H.-S. Role of chronic inflammation in cancer and metabolic diseases
Rosen, K. V. Cancer, Cell Death, Cell Signalling
Singer, R. A. Yeast Chromatin and Membrane Dynamics
Too, C. K. L. Polypeptide and Steroid Hormone Action: Tumor Growth/Apoptosis
Waisman, D. M. Mechanisms of Tumor Growth, Invasiveness and Metastases

Comparative Genomics, Proteomics & Molecular Evolution

Archibald, J. M. Genome Evolution, Endosymbiosis, Molecular Phylogeny
Blouin, C. Protein Evolution and Folding
Cohen, A.M. Development and application of mass spectrometry techniques in proteomics and metabolomics
Doolittle, W. F. Genomics, Molecular Phylogeny, Gene Transfer
Gray, M. W. Protist Genomics, Mitochondria, Ribosomes
Liu, P. X.-Q. Intein and Protein Splicing
Roger, A. J. Genome, Organelle and Protein Evolution
Slamovits, C. H. Molecular biology and evolution of microbial eukaryotes

Structure, Function & Metabolism of Biomolecules

Bearne, S. L. Enzyme Catalysis and Chemical Biology
Byers, D. M. Protein Structure and Function
Ewart, K. V. Proteostasis, Amyloid Formation and Cold Adaptation
Karten, B. Cholesterol Metabolism in the Brain, intracellular cholesterol trafficking, mitochondrial cholesterol
McLeod, R. S. Apolipoprotein B, adiponectin and fatty acids: Structure, Functio
Pulinilkunnil, T. Nutrient regulation of lysosome metabolism, signaling and autophagy in health and disease; Amino acid biology and energy metabolism
Rainey, J. K. Structural Biology and Biophysical Characterization of Proteins
Ridgway, N. D. Cell Biology of Cholesterol and Lipids
van der Spoel, A. C. Genetic Metabolic Diseases; Cell Biology of Lipids
Wallace, C. J. A. Protein Engineering: Cytochrome c

Undergraduate Education

Briggs, P. Undergraduate Biochemistry Lab Education
Ewart, K. V. Proteostasis, Amyloid Formation and Cold Adaptation