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Kyungsoo Shin


Supervisor: Jan K. Rainey
Research Area: Structural Biology and Biophysical Characterization of Proteins



HPLC, cell culture, gene expression, cloning, western blotting, mass spectrometry


Bachelor of Science Combined Honour's in Biochemistry & Molecular Biology and Microbiology & Immunology (2007-2011)
Dalhousie University
Functional characterization of apelin with varying lengths and residues

Master's in Biochemistry & Molecular Biology (in progress)
Dalhousie University

Awards & Professional Activities

Scholarships & Awards

NSERC Undergraduate Research Award (2008-2011)

Hector McInnes Memorial Scholarship (2007-2011)

Lockward Memorial Scholarship (2007-2008)

Homer Fund Scholarship (2007-2008)

Orange Scholars Scholarship (2010-2011)

Alexander Graham Bell Canada Graduate Scholarship (2012-2013)

Professional Activities

Laboratory Teaching Assistant for BIOC 3400 (2011),

Poster Presentation for Dalhousie Physiology and Biophysics Research Day (2011)

Laboratory Teaching Assistant for BIOC 3300 and 3700 (2012)

Poster for Biophysical Society 56th Annual Meeting (2012)

Presentation for IWK Obstetrics and Gynaecology Research Day (2012)

Presentation for 19th International Symposium on Regulatory Peptides (2012)


  1. Shin, K., Kenward, C. and Rainey, J.K., (2018) Apelinergic system structure and function Compr Physiol 8:407-450 [PubMed] [Article]
  2. Kenward, C., Shin, K. and Rainey, J.K., (2018) Mixed Fluorotryptophan Substitutions at the Same Residue Expand the Versatility of 19F Protein NMR Spectroscopy Chem Eur J 24:3391-3396 [PubMed] [Article]
  3. Shin, K., Landsman, M., Pelletier, S., Alamri, B., Anini, Y. and Rainey, J.K., (2018) Proapelin Is Processed Extracellularly in a Cell Line-Dependent Manner with Clear Modulation by Proprotein Convertases Peptides Revised manuscript under review:
  4. Huang, S.K., Shin, K., Sarker, M. and Rainey, J.K., (2017) Apela exhibits isoform- and headgroup-dependent modulation of micelle binding, peptide conformation and dynamics. Biochim Biophys Acta - Biomembranes 1859:767-778 [PubMed] [Article]
  5. Shin, K., Chapman, N.A., Sarker, M., Kenward, C., Huang, S.K., Weatherbee-Martin, N., Pandey, A., Dupré, D.J. and Rainey, J.K., (2017) Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands. Biochim Biophys Acta - General Subjects 1861:1901-1912 [PubMed] [Article]
  6. Shin, K., Sarker, M., Huang, S.K., and Rainey, J.K., (2017) Apelin conformational and binding equilibria upon micelle interaction primarily depend on membrane-mimetic headgroup Sci Rep 7:15433 [PubMed] [Article]
  7. Das. D., Shink, K., Rainey, J.K. and Fliegel, L., (2017) Transmembrane segment XI of the Na+/H+ antiporter of S. pombe is a critical part of the ion translocation pore. Sci Rep 7:12793 [PubMed] [Article]
  8. Pandey, A., Shin, K., Patterson, R.E., Liu, X-Q. and Rainey, J.K., (2016) Current strategies for protein production and purification enabling membrane protein structural biology. Biochem. Cell Biol. 94(6):507-527 [PubMed] [Article]
  9. Read, J., Clancy, E.K., Sarker, M., de Antueno, R., Langelaan, D.N., Parmar, H.B., Shin, K., Rainey, J.K. and Duncan, R., (2015) Reovirus FAST proteins drive pore formation and syncytiogenesis using a novel helix-loop-helix fusion-inducing lipid packing sensor PLoS Pathog 11(6):e1004962 [PubMed] [Article]
  10. Shin, K., Pandey, A., Liu, X-Q., Anini, Y. and Rainey, J.K., (2013) Preferential apelin-13 production by the proprotein convertase PCSK3 is implicated in obesity. FEBS Open Bio. 3:328-333 [PubMed] [Article]