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Seminars Archive 2012


Dr. Joel Dacks
Thursday, January 26, 2012
"And Then There Were 5: The Discovery of a New Adaptin Complex Helps Resolve the Evolution of the Eukaryotic Membrane-Trafficking System"

Dr. Andrew Rutenberg
Thursday, January 19, 2012
“Fluctuation Judo: What Photobleaching Can Tell Us About Protein Copy Numbers”

Dr. Howard Young
Thursday, January 12, 2012
"Calcium Transport in the Heart:
Structure, Function and Therapeutic Potential"

Dr. Sean Myles
Thursday, January 05, 2012
"Genomics in Medicine and Agriculture: How to Make the Most of Nature's Diversity"


Christa Moore
Thursday, February 16, 2012
"Nucleomorph Genomes: Unveiling the Disappearing Act of Nature's Smallest Nuclei"

Dr. Ryan Morin
Monday, February 13, 2012
"Integrative Genomic Analysis of Diffuse Large B-cell Lymphoma"

PhD Thesis Defence - Daniel Gaston
Thursday, February 09, 2012
"Phylogenomic Approaches to the Analysis of Functional Divergence and Subcellular Localization"

Dr. Marc Robinson-Rechavi
Thursday, February 09, 2012
"Does Gene Duplication Affect Evolution"

Dr. David Langenau
Thursday, February 02, 2012
"Fishing for Answers: Uncovering the Molecular Basis of Pediatric Sarcoma and Leukemia"


Ryan Holloway
Thursday, March 29, 2012
AEBP1 as a Novel Regulator of Sonic Hedgehog Signalling During Mammary Tumourigenesis.

Dr. Pierre Lavigne
Monday, March 26, 2012
NMR Solution Structure of STARD6 and the Cholesterol Binding Mechanism by START Domains

PhD Thesis Defence - David N. Langelaan
Monday, March 26, 2012
Structural Studies of Apelin and its Receptor as well as the Characteristics and Causes of Membrane Protein Helix Kinks

Honours Student Symposium - Session II
Thursday, March 22, 2012

Zeina Asyyed
Altered Energy Metabolism in Niemann-Pick Type C1 Deficient Glia

Amanda McLaughlin
Characterization of a Protein-Protein Interaction

Jacob Gordon
Probing the Effect of a Forbidden Pentapeptide on the Function of Saccharomyces cerevisiae iso-1 Cytochrome c

Alexandra Reda
Exploring the Interaction between PML Isoform I and Translation Factors

Van Nguyen
Addressing Ambiguities Regarding ß-Glucosidase 2: A New Player in the Metabolism of Glucosylceramide

Stephanie Allison
Overexpression of Ras leads to Increased p11 Expression and Plasminogen Activation

Honours Student Symposium - Session I
Wednesday, March 21, 2012

Ananda Koomson
Autophagy as the Regulator of Proliferation of Intestinal Epithelial Cells

Ryan Holstead
Developing a Cysteine-less GPCR

Matthew Speckert
A Positive Influence: Investigating the Importance of Key Residues Within the Apelin Peptides in the Context of the Membrane Catalysis Model

Aled Iaboni
The Role of Vav2 in Cell Spreading

Nicole Crozier
Generating a Cyan-fluorescent Genetically Encoded Calcium Indicator

Adam Aitchison
Effect of Oncogenic Ras Expression on Phosphatidyl-choline Biosynthesis

David Cho
AEBP1: a Critical Mediator in Enhancing the Inflammatory Response

Michelle Leger
Thursday, March 15, 2012
Mitochondrion Related Organelles: Common Themes in Adaptation to Anaerobiosis

Graduate Student Symposium
Friday, March 02, 2012
Hot Papers Published in Nature & Science: 2011-2012

Dr. David Hoskin
Thursday, March 01, 2012
Natural Products for
Cancer Prevention and Therapy


Second Year Graduate Student Seminars
Thursday, April 26, 2012
Tommy Harding
"Evolution on the Edge: How Protists Have Adapted to Hypersaline Environments"
---------------------------------------------- Aaron Banks
"Placing Structural Biology Results in a Physiological Context with Experimentally Informed Computation"

Second Year Graduate Student Seminars
Thursday, April 19, 2012
Kathleen Attwood
Ph.D. Candidate

"Effect of Chromatin Structure and the Subnuclear Localization of a DNA Break on the Progression of DNA Repair"
Aditya Pandey
M.Sc. Candidate

"Structural Characterization of Proapelin and Apelin Receptor"

Second Year Graduate Student Seminars
Thursday, April 12, 2012
Rafaela Andrade-Vieira
Ph.D. Candidate

"The Effects of Polyunsaturated Fatty Acids on Cell Signalling"
Jose Sergio Hleap
Ph.D. Candidate

"Shaping Proteins Shapes: A Composite Approach To Protein Structure Evolution"

Dr. Stephen Montgomery
Thursday, April 05, 2012
"Genetics of Gene Expression Using Next Generation Sequencing"


Dr. Edward Pryzdial
Thursday, May 24, 2012
Clotting Proteases Activated and Exploited by Enveloped Viruses

Second Year Graduate Student Seminars
Thursday, May 03, 2012
Mandar Khanal
M.Sc. Candidate

Inhibition of Prostate Cancer Biomarker α-Methylacyl-CoA Racemase (AMACR) by a Novel Substrate Analogue
Samir Koirala
M.Sc. Candidate

Androgen Regulation of Gene Expression & Transcription in Breast Cancer Cells


Dr. Chris Loewen
Thursday, June 14, 2012
Lipid pH Biosensors and Biogenesis of the Endoplasmic Reticulum in Yeast

Dr. Anna Gubskaya
Thursday, June 07, 2012
Computer-aided Molecular Design in Biomedical Research


MSc. Thesis Defence - André Dubé
Tuesday, August 21, 2012
Investigation of Antifreeze Protein Activity in Blue Mussels and Amyloid-Like Transition in a Predominant Winter Flounder Serum Antifreeze Protein

MSc. Thesis Defence - G. McCluskey
Friday, August 17, 2012
AEBP1 Alters Matrix Signalling and it is Responsive To Inflammation in the Mammary Gland


Dr. Gary Shaw, Professor
Thursday, September 27, 2012
Structure and Mechanism of Parkin, an E3 Ligase Linked to Parkinson's Disease

Dr. David Waisman, Professor
Thursday, September 20, 2012
A Catastrophic Collaboration; S100A10 Facilitates the Tumor Promoting Association of Macrophages with Cancer Cells

MSc Thesis Defence - Javier Alfaro
Tuesday, September 18, 2012
Capturing the dynamics of protein sequence evolution through site-independent structurally constrained phylogenetic models

Dr. Sultan Darvesh, Professor
Thursday, September 13, 2012
Butyrylcholinesterase as a Diagnostic and Therapeutic Target in Alzheimer's Disease


Picchione Visiting Scholar - Dr. Neil Cashman
Thursday, October 25, 2012
Borrowing from the Prion Playbook: Propagated Protein Misfolding and Novel Targets for Neurodegeneration

Ph.D. Thesis Defence - Bruce Curtis
Monday, October 22, 2012
Endosymbiotic Gene Transfer in the Nucleomorph Containing Organisms Bigelowiella Natans and Guillardia Theta

Dr. Jeremiah Hackett
Monday, October 22, 2012
Selection and Gene Transfer in the Evolution of Novel Traits in Microbial Eukaryotes.

2011/12 Doug Hogue Award Recipient - Courtney Stairs
Thursday, October 18, 2012
Metabolic Novelty in the Mitochondrion-Related Organelles of “Beckamonas Plexus”: A Pathway Disappearing Act

Dr. John Honek
Thursday, October 11, 2012
Structure and Function of the Glyoxalase Metalloenzymes

Dr. Donald Weaver
Thursday, October 04, 2012
Designing Disease Modifying Molecules for Chronic Neurodegenerative Disorders


Dr. Alejandro Cohen
Thursday, November 29, 2012
The Promises, Pitfalls and Paraphernalia of Quantitative Proteomics'... Now Playing in Your Local Research

M.Sc. Thesis Defence - Ryan Holloway
Tuesday, November 27, 2012
Macrophage AEBP1 Contributes to Mammary Epithelial Cell Hyperplasia as a Novel Regulator of Shh Signalling

Dr. Michel Grandbois
Thursday, November 22, 2012
AFM-Based Force Sensing on Individual Cells; Applications in Pharmacology

Dr. Tak Mak
Tuesday, November 20, 2012
Future Anti-Cancer Targets:
Put the Cart Before the Horses

2 Graduate Students & 2 Honours Students
Thursday, November 15, 2012
M.Sc. Candidates Manoj Hariharan “Effects of insulin on synapse formation and function; Is insulin a double edged sword?” Kyungsoo Shin “The Adipokine Apelin, Inhibitor of Adipolysis, is Processed by the PCSK Furin” Honour Students Wilson Chan “Testing for Modularity in Protein from Molecular Dynamics Simulation” Matthew Foss “Exploring the Role of Vav2 in Cell Migration”

Dr. Paul Linsdell
Thursday, November 08, 2012
Transport Mechanism of CFTR, a Unique ABC Transporter Protein

Dr. Christa Brosseau
Thursday, November 01, 2012
Electrochemical Surface Enhanced Raman Spectroscopy (E-SERS): A Plasmonic tool for Biochemistry


M.Sc. Thesis Defence - Manoj Hariharan
Wednesday, December 05, 2012
Effects of Insulin on Synapse Formation and Function; A Possible Role for Insulin Resistance