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Seminars Archive 2018

January

Dr. Derek Wilson
Wednesday, January 31, 2018
Linking Protein Conformational Dynamics with 'Real World' Drug Development
in Neurodegenerative Disease and Cancer

February

Dr. Gilbert Walker
Wednesday, February 14, 2018
Hydrophobic hydration

The interactions of hydrophobes with water, each other and surfaces drives many interesting processes, ranging from protein collapse, ligand binding and cellular attachment. Hydrophobe size matters, and there appears to be a fundamental transition from volume to surface area control of the hydrophobic hydration energies as size increases. I will illustrate how the macromolecule structure change is induced at these different length scales, with examples taken from single proteins, amyloids, polymers, and their surfaces. Finally, I will give examples of applications of these concepts to create materials for biodiagnostics and biofouling control.

Dr. Brendan Leung
Wednesday, February 07, 2018
Towards disease-on-a-dish: applications of microtissues and micropatterning technologies in advanced culture and assay platforms

March

Honours Student Research Presentations 2018
Wednesday, March 28, 2018
Honours Student Research Presentations 2018

Dr. Andrew M. Gulick
Friday, March 23, 2018
Multiple Strategies for Iron Acquisition: Biosynthesis of Siderophores using Assembly Lines or the Old Fashioned Way

Ph.D. Thesis Defence - Gregory D. McCluskey
Thursday, March 22, 2018
Investigation of Inhibition, Filament Formation, and Inter-Domain Ammonia Channelling of CTP Synthase

Dr. Christopher Beh
Wednesday, March 21, 2018
Membrane In - Membrane Out: Coordinating Transport to the Cell Membrane

Ph.D. Thesis Defence - Antonietta Pietrangelo
Tuesday, March 20, 2018
ORP4 is a Phospho-regulated Lipid Binding Protein Required for Cell Growth and Maintenance of TGN Morphology

Graduate Student Symposium
Wednesday, March 14, 2018
Biochemistry 5910.06

Dr. Lewis Kay, 2017 Canada Gairdner International Laureate
Wednesday, March 07, 2018
NMR Why Bother? Studies of the p97 Molecular Machine Provide an Answer

April

Dr. Gregory Steinberg
Wednesday, April 18, 2018
Cellular energy sensing and metabolism: implications for treating diabetes

2016 Patrick Prize Award Seminar - Dr. Mitesh Nagar
Wednesday, April 11, 2018
Finding keys to the “PAD”lock: Unraveling the regulation of Protein Arginine Deiminases

Dr. Robert Beiko
Wednesday, April 04, 2018
Mining Antimicrobial-Resistance Genes From Metagenomic Data

May

Jonghwa (Kyle) Lee, Ph.D. Candidate
Wednesday, May 23, 2018
The role of phosphatidylcholine in lipid droplet biogenesis and lipoprotein secretion

Sarah Shah & Michael McPhee, M.Sc. Candidates
Wednesday, May 16, 2018
Sarah Shah
“The mitochondrial genome of Blastocystis sp. isolated from the Oriental cockroach”

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Michael McPhee
“Understanding the role of phosphatidylcholine biosynthesis in cancer cells.”

Macpherson Seminar
Monday, May 14, 2018

Speakers

10:00 a.m.

Discovery and development of Selonsertib, a first in class inhibitor of ASK1 for the treatment of nonalcoholic steatohepatitis


Dr. David Breckenridge

Senior Director of Biology, Gilead Sciences Inc.
4:00 p.m.

Three short stories on survival in the age of CRISPR/Cas9


Dr. David Edgell

Acting Chair, Department of Biochemistry, Western University

Dr. L. B. Macpherson taught biochemistry at Dalhousie University for sixteen years and played a major role in the development of the Medical School.